Neo Fertility can eliminate Pre Menstrual Syndrome in the majority of women. It is common to have negative symptoms for 2 or even 3 days pre menstruation and this is not a huge concern – but if you have symptoms such as bloating, breast tenderness, mood changes etc for a week or more each cycle before menstruation this is a concern. Apart from feeling unwell, it is associated with a higher incidence of infertility and miscarriage. PMS is multifactorial, so several underlying factors can contribute to it and cause it to be problematic. A significant majority will feel dramatically better following treatment with low dose naltrexone which stimulates endorphin levels and relieves negative symptoms over 70% of the time.